After one week she get swelling face, and leaking eye. (Note: Do not remove syringe while bottle is inverted as spillage may result.) Detach syringe and administer solution orally at the rate of 1 mL per 110 pounds body weight (0.044 mg/kg) once daily for 15 consecutive days. Lost over $300 including cost of gun. Further, it is considering also prohibiting the use of a stronger progestin, Altrenogest or Regumate, in all geldings and stallions. Oral altrenogest is no longer under patent, and is … Regumate® is the trade name for a synthetic hormone called altrenogest. Positude helps address the behavioral side effects associated with the estrus cycle. One is designed to last 7- 10 days and the other is a 30 day treatment. Regumate is the trade name for a synthetic hormone called altrenogest. Suppression of estrus will also facilitate management of prolonged estrus conditions. Regu-Mate (altrenogest) Solution 0.22% is indicated to suppress estrus (period of the reproductive cycle when the mare ovulates and, if bred, is likely to conceive) in mares. Yes. Who is Regu-Mate Solution for? Regumate is one of a handful of products used to regulate the period cycles of fillies and mares and those cycles are most disruptive in the spring. The proper use of progesterone and Regumate® requires understanding the hormones actions. It is also commonly used to help maintain pregnancy in mares determined to be at risk of pregnancy loss. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. Altren® is manufactured in Minnesota in a GMP facility registered with FDA. The same formulation and active ingredient a Regu-Mate®. Regumate may be necessary for the real problem mares that are unpredictable, have wide mood swings and exhibit excessively strong estrus periods, although we would consider herbal preparations first, particularly if this is a high-performance mare. If the owner does not want to give the oral altrenogest daily, there are injectable altrenogest products that are compounded. Customers also viewed these products. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. Skin contact must be avoided; protective gloves must be worn when handling this product. It may be used to suppress and prevent the signs of oestrus in mares, which may be particularly useful early in the breeding season. REGUMATE IN STALLIONS – Effects on Reproductive Performance Patrick M. McCue DVM, PhD, Diplomate American College of Theriogenologists Regumate® or altrenogest is a synthetic progestin approved for suppression of estrus in mares. Direct contact with the skin should be avoided. The Dial-A-Dose system (2mL to 15mL) allows for an easy setting of dosage and accuracy of dosage. Positude helps address the behavioral side effects associated with the estrus cycle. “Regumate Equine 2.2 mg/ml oral solution for horses is indicated for mares to facilitate breeding. The Regumate Dosing Device is easy to dismantle for cleaning and re-lubrication. Pregnant women or women who suspect they are pregnant should not handle Regu-Mate… Administer solution directly on the base of the mare's tongue or on the mare's usual grain ration. Regumate Porcine uses ORAL PROGESTIN SOLUTION 0.22% (2.2 mg/mL) FOR USE IN ANIMALS ONLY For suppression of estrus in mares. Regu-Mate® is contraindicated for use in mares having a previous or current history of uterine inflammation. Regu-Mate is a solution for oral use only and is available in a 1,000 ml bottle. When you stop, she'll probably come into heat within five to 10 days. Meat and offal: 15 days. For owners or exhibitors of mares, you will be limited to the use of Regumate to control estrous. Oral altrenogest is no longer under patent, and is … It is intended for use in non-food animals only. Regumate Equine is a hormonal treatment for mares containing the synthetic progestagen altrenogest. Simply apply the Regu-Mate solution at either the base of the mare's tongue or directly on her grain. Available in 1000 mL bottles along with a dispensin cap. She had been having intermittent behavior and stiffness issues that after seeing several vets could not be attributed to any lameness issues. Always wear protective gloves when administering Regu-Mate®. I have seen these mares go through dripping sweats, muscle tremors, etc etc. Right now not looking at marble. Trust the original altrenogest solution for horses. Mares on Regumate to maintain pregnancy can have their progesterone level drawn to see if she needs to continue on the regumate as the reugmate is synthetic and not recognized by the test, thus the actual level indicated by the test is the true reading that the pregnancy is producing. Which is when Peters will bring his superstar mares ARCADIA QUEEN and ENTICING STAR to the east coast. ReguMare helps support the normal hormonal balance of your mare when temperament and marish behaviour adversely affects safe handling, willingness to work and performance. If you start it during diestrus, it will prevent your mare from returning to estrus as long as she continues to get a daily dose. Regu-Mate provides safe, effective suppression of estrus in mares - 95% effective after 3 days of treatment. Dolorex® (butorphanol tartrate injection), Protazil® (1.56% diclazuril) Antiprotozoal Pellets, Trust genuine REGU-MATE® (altrenogest) Solution 0.22% for proven palatability, bioavailability and efficacy in every dose, The only FDA-approved altrenogest with more than 50 million doses sold, Delivers safe, predictable control over a mare’s reproductive cycle and reduces undesirable mood and behavioral changes, 15-day treatment regimen lets performance mares compete at their best, Strategic use helps accommodate mare’s performance schedule, Easy-to-administer with REGU-MATE® dosing device. This product is contraindicated for use in mares with a previous or current history of uterine inflammation. Pregnant women, or women who suspect they are pregnant, should not handle this product. I am not at all a fan of regumate. “Mares generally do not cycle year-round,” he continues. Vet is coming tomorrow to look at another horse so I wanted to be able to ask him about different treatment options. One is designed to last 7- 10 days and the other is a 30 day treatment. Copyright © 1995-2020 Intervet Inc., doing business as Merck Animal Health, a subsidiary of Merck & Co., Inc. All rights reserved. Toggle navigation 76. Regu-Mate Solution Indicated to suppress estrus in mares. Regu-Mate requires a prescription from your veterinarian. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. Page 1 of 1 Start over Page 1 of 1 . Regumate is designed to prevent a mare from cycling, but Positude is not. Regu-Mate Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. To understand fully how these drugs work, first, let’s briefly review the science behind mares’ cycles—when they happen and why. PRECAUTIONS Various synthetic progestins, including altrenogest, when administered to rats during the embryogenic stage of pregnancy at doses manyfold greater than the recommended equine dose caused fetal anomalies, specifically masculinization of the female genitalia. Draw out appropriate volume of Regu-Mate® solution. 15-day treatment regimen allows performance horse to compete at their best. It is meant to be used for the suppression of estrus in mares. Intervet Inc. d/b/a Merck Animal Health, Madison, NJ 07901, Better mare management: How to manage broodmares and performance mares more efficiently, When everything is at stake, trust Regu-Mate, Unwanted Horse Veterinary Relief Campaign (UHVRC), American Association of Equine Practitioners (AAEP), American Association of Equine Veterinary Technicians and Assistants (AAEVT), American College of Veterinary Internal Medicine (ACVIM), Northeast Association of Equine Practitioners (NEAEP), Texas Equine Veterinary Association (TEVA), United States Eventing Association (USEA), The only FDA-approved altrenogest with more than 20 million doses sold, Delivers safe, predictable control over a mare's reproductive cycle and reduces undesirable mood and behavioral changes, 15-day treatment regimen lets performance mares compete at their best, Strategic use helps accommodate mare's performance schedule, Easy to administer with Regu-Mate dosing device. Hi I have a mare who can be extremly unpredictable (when ridden) and very marish (pulling faces, threateneing to kick etc) when coming into/ having a season and last year I put her on regumate after speaking to the vet and after trying herbal feed supplements (and after having a physio and dentist check her just incase there was anything underlying there etc). Helps reduce sensitivity to being groomed or tacked-up. Most people find that Positude is so effective in addressing their mare’s behavior that they do not need Regumate, but it is ok to use both. Mare is not moody but seems to be in heat more frequently then usual and doesn't want to run or get down in turns when she is in. WARNING Regu-Mate® (altrenogest) Solution 0.22% is readily absorbed by the skin. Mares have been given Regumate for up to 60 days and then bred with no adverse effect on fertility. Most people find that Positude is so effective in addressing their mare’s behavior that they do not need Regumate, but it is ok to use both. Protective gloves must be worn by all persons handling this product. Protective gloves should be worn when handling product; women who are pregnant or suspect they are pregnant should not handle Regu-Mate Solution 0.22%. The usual dose is 1 ml per 110 lbs body weight once daily for 15 consecutive days. “Often mare owners/riders are quite happy with their mares’ behavior in late fall, winter, and early spring. Remove cover from bottle dispensing tip and connect luer lock syringe (without needle). How soon normal oestrus cycles will return post-treatment will again depend on the ovarian activity of the individual mare … Regu-Mate ® (altrenogest) Solution 0.22% is indicated to suppress estrus in mares. We just started my mare on 3 ml of im altrenogest that she gets once a week for four weeks and then possibly reduced down to every three weeks - I THINK this is the p+, but I'm wondering how such a low dose works and how it is different from the p4 ( which I know nothing about) and the boirelease. Regumate may be used to manage the behaviour of mares that exhibit prolonged oestrus cycles, supressing oestrus in mares that display undesirable behavioural changes. Regumate Equine is used to control oestrus ("heat") in mares. We just started my mare on 3 ml of im altrenogest that she gets once a week for four weeks and then possibly reduced down to every three weeks - I THINK this is the p+, but I'm wondering how such a low dose works and how it is different from the p4 ( which I know nothing about) and the boirelease. The cost-effective alternative to Regu-Mate®. Regu-Mate (altrenogest) Oral Progestin is indicated to suppress estrus in mares. Regumate and Positude are different. Mares have been given Regumate for up to 60 days and then bred with no adverse effect on fertility. Regumate (altrenogest) appears to be the safest way to go when seeking to prevent a mare from coming into heat, says Beckman, although it does have a downside--it is expensive. For mares that aren't cycling normally, putting them on regumate for 14 days and then taking them off can help them come into a normal heat. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Administer orally with dose syringe or by placing directly on feed. Each ml contains 2.2mg altrenogest. Had to go buy new prescription and will never use gun again. While wearing protective gloves, remove shipping cap and seal; replace with enclosed plastic dispensing cap. Simply apply the Regu-Mate solution at either the base of the mare's tongue or directly on her grain. Another fact: At present, USEF is considering a future ban on the use of Depo- Provera in all horses. Replace cover on bottle dispensing tip to prevent leakage. DosageWhile wearing protective gloves, remove shipping cap and seal; replace with enclosed plastic dispensing cap. Skin contact must be avoided; protective gloves must be worn when handling this product. The classic method is daily oral administration of the progestin altrenogest (e.g., Regu-Mate). Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Each ml contains 2.2mg altrenogest. And it improves most mares on the racetrack who are on it. It can be given directly by mouth or on your mare's grain ration. Each ml of Regu-Mate Solution contains 2.2 mg altrenogest oral progestin. REGU-MATE® (altrenogest) Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation. For mares that have low progesterone levels after they've conceived, it can help them keep their hormone levels high enough to maintain a pregnancy until their body starts manufacturing on their own. Regumate® is occasionally administered off-label to stallions in an attempt to suppress undesirable male behavioral characteristics When treatment is discontinued, mares exhibiting regular estrous cycles return to estrus within 4 to 5 days following treatment and continue to cycle normally.